Maxwell O Adibe1
,
Aminu A Biambo2,
Abdulmuminu Isah1,
Aliyu Samaila2,
Nuruddeen Usman2
For correspondence:- Maxwell Adibe Email: maxwell.adibe@unn.edu.ng Tel: +2348037781479
Published: 31 December 2016
Citation: Adibe MO, Biambo AA, Isah A, Samaila A, Usman N. Evaluation of drug therapy problems among patients receiving care in National Orthopedic Hospital in Nigeria. J Sci Pract Pharm 2016; 3(1):105-114 doi: 10.47227/jsppharm.v3i1.5
© 2016 The author(s).
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Purpose: Drug Therapy Problems (DTPs) are common in hospitals, especially those that are resource limited, leading to a wide range of clinical and economic implications. The purpose of this study was to evaluate the profile of drug therapy problems, causes, intervention and outcomes of interventions
Methods: This retrospective study involved the review of 6 years DTP records of the National Orthopedic hospital, Enugu. The Drug Related Problem instrument (version 5) by Pharmaceutical Care Network Europe was used. DTP record of 2009 to 2012 was reviewed, analysed and categorized into problems, causes, interventions, and outcomes of interventions. The results were presented in frequencies and percentages.
Results: A total of 343 DTPs were identified from 83 different drugs. The mean age of the patients was 30.23±25.86 years. Prescription only medicines (75%) were the most encountered. Antibiotics and analgesic contributed 64.7% of all the DTPs identified. About half (49.3%) of the DTPs identified were as a result of dosing problems. Poor Drug/Dose selection accounted for more than half (53.1%) of the causes of DTPs. Intervention was highest (43.3%) at prescriber level. Reasonable number of the intervention proposed was approved by the prescribers (54%). Most of the DTPs identified (63.8%) were totally resolved.
Conclusion: There was high prevalence of DTPs among the patients. Problems were mostly as a result of dosing errors while the major cause was poor Drug/Dosage selection. Intervention was highest at prescriber level. A reasonable number of the intervention proposed was approved by the prescribers and most of DTPs identified were totally resolved
